| Home | E-Submission | Sitemap | Contact us |  
top_img
Kor J Aesthet Cosmetol > Volume 2(1); 2004 > Article
화장품 원료개발을 위한 파리유충과 土龍추출물의 생리활성기능 조절에 관한 연구
장문정, 안명수
Stuies on the Bioactivity Modulation of Maggot and Earthworm Extracts for the Development of Cosmetic Resources
Moon-Jung Chang, Myung-Soo Ahn
ABSTRACT
The present study was undertaken to develop the available resources for cosmetics including health foods or medicine from natural resources. The biofunctional activities such as anti-microbial activity, antioxidation activity, and immune modulation activity were investigated by using several extracts from earthworm, maggot and seaweeds. In results, anti-microbial or anti-bacterial activities of extracts from maggots and earth worms, both hot water and solvent extracts showed high anti- microbial activities against Streptococcus, g(+), Salmonella, choleraesuis subup. g(-), Pseudomaonas aeruginosa g(-), Escherichia coli. g(-), Bacillus subtilis g(+). Meanwhile, the earthworm including intestine contents was extracted with ethanol, anti-microbial activity was not observed against Pseudomonas aeruginosa g(-). In case of Escherichia coli. g(-), anti-microbial activity was only observed in the earthworm extracts excluding intestinal contents. Furthermore, the anti-microbial activity of earthworm extracts against fungus such as Staphylococcus warneri, Staphylococcus xylosus and Staphylococcus hominis subup. Hominis, was only found in the extracts including intestinal contents. In case of extracts of earthworm excluding intestinal contents, both hot water and ethanol extracts showed strong anti-microbial activity against Staphylococcus warneri, but no anti-microbial activity was observed against Staphylococcus xylosus. Anti-microbial activity against Staphylococcus hominis subup. hominis was found only in the group treated with the extracts of earthworm excluding intestinal by ethanol. The maggot extracts showed the clear increase of proliferation activity at the level of 100ppm, but the higher concentration of maggot extract showed the lower proliferative activities, and cytotoxic effect was observed in splenocytes treated with over 5000ppm of maggot extract. Meanwhile, when splenocytes were treated with 100ppm and 500ppm of earthworm extracts, the proliferation activity was increased in dose dependent manner. In the results of antioxidation activities of maggot and earthworm extracts, DPPH production was not inhibited by earthworm extracts but maggot extracts showed significant inhibitory effects of DPPH production as much as 50% of Vitamin C when treated with 10000ppm. It has been thought that the comparatively lower effects of earthworm extracts on DPPH inhibition may be due to the lower concentration of responsible compound in the extracts. Likely the case of DPPH inhibition, the earthworm extracts did not show any inhibitory effects on TBARS. In summary, the extracts of maggot, seaweeds and earthworm showed increased anti-microbial activities, anti-oxidative function and immune modulation activities. All together, it has been suggested that the extracts from natural product such as maggot and earthworm can be developed and used for functional substances in the fields of cosmetics.
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
Share:      
METRICS
718
View
5
Download
Related article
Editorial Office
No.306, 244 Beotkkot-ro, Geumcheon-gu, Seoul 08513, Republic of Korea
TEL: +82-70-7707-4346   FAX: +82-502-770-2278   E-mail: ajbc.edit@gmail.com
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korea Institute of Dermatological Sciences. All rights reserved.