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Kor J Aesthet Cosmetol 2015;13(4): 469-476. |
| 마늘추출물 함유 화장료의 피부 기능성 효과 : 항산화 및 콜라게나제, 엘라스타제와 티로시나제의 억제 효과를 중심으로 |
| 김영숙, 정은영, 고혜정, 홍양희 |
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| Effects of Formulation Containing Garlic Extract on Functional Skin Care: Antioxidation and Inhibitive Activities of Collagenase, Elastase and Tyrosinase |
| Young Suk Kim, Eun Young Jung, Hyea Jung Koh, Yang Hee Hong |
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| ABSTRACT |
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We was to evaluate the physiological effects of formulation containing garlic extract on skin care. The total polyphenol (p<.001), flavonoid (p<.001) contents and 1,1-diphenyl–2-picrylhydrazyl (DPPH) (p<.001), 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) (p<.01) radicals scavenging activities and reducing power (p<.05) of the garlic formulation were significantly higher compared to those of the base formulation. The inhibition of collagenase (p<.05) of the garlic formulation were significantly higher compared to those of the base formulation. Specially, the base formulation inhibited slightly elastase activity whereas the garlic formulation had about 8-fold higher elastase inhibitory activity (p<.001). When the garlic extract was added to the formulation, the tyrosinase activity was decreased significantly (p<.05, p<.01, p<.001). In conclusion, the garlic formulation had high inhibitory activities for tyrosinase and elastase, thus suggesting that garlic may have beneficial properties as a material for cosmeceuticals. |
| Key words:
Garlic formulation, Antioxidant effects, Collagenase, Pancreatic elastase, Tyrosinase
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