| 살리실산, 글루코노락톤, 나이아신아마이드를 함유한 클렌저 제품의 여드름 방지 및 내약성 평가 |
| 조우1,2,3, 예운비4 |
1상하이 교통대학교 의과대학 신화병원 피부질환 진단 및 치료센터, 상하이, 중국
2상하이 교통대학교 부속 신화병원 피부과, 상하이, 중국
3상하이 교통대학교 의과대학 피부과 연구소, 상하이, 중국
4로레알 중국 피부과 및 미용 사업부, 상하이, 중국 |
| Anti-acne and Tolerance Assessment of a Cleanser Containing Salicylic acid, Gluconolactone and Niacinamide |
| Yu Cao1,2,3, Yunfei Ai4 |
1Dermatology Center, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
2Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
3Institute of Dermatology, Shanghai Jiaotong University School of Medicine, Shanghai, China
4L'Oréal (China) Co., Ltd., Shanghai, China |
| 针对含有水杨酸、葡萄糖酸内酯和烟酰胺洁面产品的抗痘和耐受性评估 |
| 曹宇1,2,3, 艾云飞4 |
1上海交通大学医学院附属新华医院皮肤疾病诊治中心，上海，中国
2上海交通大学附属新华医院皮肤科，上海，中国
3上海交通大学医学院皮肤病研究所，上海，中国
4欧莱雅中国皮肤科学美容事业部，上海，中国 |
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Received: March 10, 2024; Accepted: September 5, 2024. Published online: September 27, 2024. |
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| ABSTRACT |
Purpose:
Acne has potential to cause psychological distress and significantly diminish one's quality of life. Although washing and over-the-counter cleansers are commonly used in the treatment of acne vulgaris, clinical evidence supporting their effectiveness is still limited. The main focus of this research is to explore anti-acne effectiveness and mildness of a cleanser containing salicylic acid, gluconolactone, and niacinamide.
Methods:
We recruited two groups of participants. One group consisted of 43 individuals with oily acne-prone skin, and we measured their inflammatory lesions, non-inflammatory lesions, and sebum content after 4 weeks of product usage. The other group included 39 individuals with sensitive skin, and we assessed objective irritation parameters and subjective irritation parameters after 2 weeks’ product usage.
Results:
After 4 weeks of using cleanser containing retinol, niacinamide and ceramides on oily acne-prone skin, significant reductions were observed in both inflammatory acne lesions count and non-inflammatory acne lesions count, while there was also a significant decrease in skin sebum content. After two weeks of use on sensitive skin, significant improvements were observed in both subjective and objective irritation parameters.
Conclusion:
In summary, a cleanser containing salicylic acid, gluconolactone and niacinamide can effectively improve acne symptoms while being gentle enough for use on sensitive skin. |
| Key words:
Cleanser, Acne, Sensitive skin, Salicylic acid, Niacinamide |
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