| Research Article |
| Antioxidant Activity and Inhibitory Effects of Fermented Lavandula angustifolia Flower Extract on UVB-Induced Skin Aging |
| Nanyoung Paek1, Su-Mi Cha2, Myung-Ja Cho3,4, Jeong-Dan Cha3,5 |
1Semiwon Foundation, Yangpyeong-gun, Gyeonggi-do, Korea
2Department of Oral Microbiology, School of Dentistry, Chonbuk National University, Jeonju-si, Jeonbuk State, Korea
3Department of Forest Healing, Jeonju Kijeon College, Jeonju-si, Jeonbuk State, Korea
4Agricultural Corporation Hwanggeumui Sup, Jeonju-si, Jeonbuk State, Korea
5The Korea Traditional Onggi Fermentation Healing Food Association, Jinan-gun, Jeonbuk State, Korea |
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Received: May 25, 2026; Accepted: August 3, 2026. Published online: August 4, 2026. |
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| ABSTRACT |
Purpose:
This study investigated the antioxidant and anti-photoaging activities of water extract (LAFDE), 50% ethanol extract (LAFEE), and fermented extract (LAFFE) prepared from Lavandula angustifolia flowers and evaluated their potential as functional cosmetic ingredients.
Methods:
Antioxidant activities were determined by measuring total polyphenol and flavonoid contents as well as DPPH and ABTS radical scavenging activities. Anti-photoaging effects were evaluated in UVB-irradiated HaCaT keratinocytes by assessing elastase inhibition, type I procollagen production, matrix metalloproteinase (MMP) expression, and skin barrier- and hydration-related gene expression.
Results:
Among the tested extracts, LAFFE exhibited the highest levels of total polyphenols and flavonoids and demonstrated the strongest radical scavenging activities. In UVB-irradiated HaCaT cells, LAFFE significantly increased elastase inhibitory activity and type I procollagen production in a concentration-dependent manner. Moreover, LAFFE markedly reduced MMP-1 production and suppressed the mRNA expression of MMP-3, MMP-9, and MMP-13, which are closely associated with collagen degradation and skin photoaging. In addition, LAFFE enhanced the expression of skin barrier- and moisturizing-related genes, including filaggrin (FLG), keratin 1 (KRT1), hyaluronan synthase 2 (HAS-2), hyaluronidase 3 (HYAL3), and aquaporin 3 (AQP3).
Conclusion:
These findings indicate that fermented L. angustifolia flower extract possesses potent antioxidant, anti-wrinkle, and skin barrier-enhancing activities. Therefore, it may serve as a promising natural cosmetic ingredient for preventing UVB-induced skin photoaging and improving skin health. |
| Key words:
Lavandula angustifolia, Fermented extract, Antioxidant activity, Photoaging, Skin barrier function, Functional cosmetic ingredient |
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