| 함초와 발효 함초 추출물의 화장품 소재로서 생리활성 비교연구 |
| 오수정, 모정희 |
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| A Comparative Study on Bioactivity of Dried and Fermented Salicornia Herbacea Extracts as Cosmetics Materials |
| Su-Jeong Oh, Jeong-Hee Mo |
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| ABSTRACT |
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This study aims to discover a possibility that ethanol and methanol extracts of dried and fermented
Salicornia herbacea can be used as materials of cosmetics through bioactivity such as cytotoxicity,
whitening activity, and antioxidation. As a result of the cytotoxicity which was carried targeting
Raw 264.7 cell leave, it was discovered that there was no cytoxicity from the four extracts
as cell survival rates of all the extracts were 106～133%. When the tyrosinase inhibitory activity for
whitening was measured, all the four extracts had high inhibitory activity according to concentration
and the inhibitory activity of ethanol extract of fermented S. herbacea was the highest. When DPPH
radical scavenging effect for antioxidation was measured, the scavenging effect of ethanol extract of
fermented S. herbacea was the highest. In particular, in comparison with antioxidative effect of BHT
SC50 of 1.29 ㎎/㎖, that of fermented S. herbacea was similar, which indicates that it has a relatively
high antioxidative effect. Therefore, as it was demonstrated that S. herbacea, methanol and ethanol
extracts of fermented S. herbacea had no toxicity as materials of cosmetics and of the four specimens,
ethanol extract of fermented S. herbacea has the highest in cytotoxicity, tyrosinase inhibitory
effect and DPPH radical scavenging effect, its possibility to be used as a material of fermented cosmetics
was confirmed. |
| Key words:
Antioxidative, Dried Salicornia herbacea, fermented S. herbacea, MTT, Tyrosinase |
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