|
Kor J Aesthet Cosmetol 2010;8(3): 71-80. |
| MYC 추출물이 고지방식이를 급여한 Zucker rats의 콜레스테롤 저하 및 비만 억제에 미치는 영향 |
| 이혜숙, 황석연 |
|
| Effect of MYC Extracts on Cholesterol-lowering and Anti-obesity Effects in Zucker rats Fed a High-Fat Diet
|
| Hye-Sook Lee, Seock-Yeon Hwang |
|
|
|
|
|
|
| ABSTRACT |
|
The aims of this study were to evaluate the anti-obesity of MYC extracts in male Zucker fa/- rats fed high rat diets for 8 week. Experimental groups were divided into 5 groups; a normal diet group(ND), a high fat diet group(HFD), a high fat diet and MYC extracts 1% group(HFD+MYC 1%), a high fat diet and MYC extracts 3% group(HFD+MYC 3%) and a high fat diet and MYC extracts 5% group(HFD+MYC 5%). The body weight gain, liver and epididymal adipose tissue weights of HFD group were heavier than those of ND group, whereas those of groups administered MYC extracts were gradually decreased. The concentration of serum triglyceride and total cholesterol were significantly decreased in high fat diet and MYC extracts groups compared to HFD group. Levels of total cholesterol, lipid and bile acid in liver were significantly lower in MYC extracts administration groups than those in HFD group. Levels of total cholesterol, lipid and bile acid in feces were significantly higher in MYC extracts administration groups than those in HFD group. These results suggest that oral feeding of the MYC extracts may have anti-obesity effect by suppressing body weight gain, liver, epididymal adipose tissue weights and lipid metabolism of serum.
|
| Key words:
MYC extracts, Zucker fa/- rats, Cholesterol, Anti-obesity
|
|
|
|
PDF Links
Full text via DOI 
Download Citation 
E-Mail 
