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Kor J Aesthet Cosmetol > Volume 12(1); 2014 > Article
Kor J Aesthet Cosmetol 2014;12(1): 17-24.
천연추출물을 이용한 발모 및 두피 개선에 관한 연구 동향
Research Trends Relevant with Hair Growth Promotion and Scalp Condition Improvement by Applying Natural Extracts
Kyung-Suk Kim
These days, the population who is suffering from hair loss resulted from variation of genetic, social, and cultural factors has increased. However, according to researches, medicinal therapy accompanies demerits of various side effects and requires to take a long period of time. Therefore, for mineralizing the demerits, lots of researches have engaged with application of natural objects. This research aims not only to explore research trends relevant with hair growth and scalp improvement by applying safe natural extracts but also to suggest a basic material which reports natural extracts having hair growth promotion effect. Among aroma essential oils, hair growth promotion effect can be found in a peppermint and a rosemary. Futhermore, the peppermint shows an excellent effect against dandruff bacillus. Also the promotion effect can be found in sandalwood and rose absolute, which is proved by hair production and increased number of hair follicle. Among plant extracts, the promotion effect can be found in polygoni mulitiflori radix water extracts, which is proved by thickened thickness of dermis, increased number of hair follicle, deepen depth of hair follicle. Applying wild cultivated ginseng results in increased number of hair, thickened thickness of hair, as well as enhancement of hair density. The wild cultivated ginseng plays a prevention role against death of hair follicle cells and play a promotion role to regeneration of that. And the general ginseng plays a promotion role for hair cell growth. Wild ginseng roots extracts has hair growth promotion effect and presents high manifestation of VEGF, IGF-1, besides has an anti-bacterial effect against dandruff bacillus. Sparassis crispa presents hair growth promotion in the group of water fraction of sparassis crispa extract, which means there is increased number and deepen depth of hair follicle. A herbral product (DCS-HT®), which is composed of mulberry root extract and polygoni mulitiflori radix water extracts and β-sitosterol at the 1:1:3 proportion, presents hair growth promotion effect, activation of ALP, γ-GT enzyme, and high manifestation of IGF-1, TGF-β. Applying acetone extract makes hair growth in the EtoAc fractionation and hair follicles occurrence in the hypoderma. Applying phellinus linteus extract leads to reduction of testosterone and DHT consideration in blood and increase of hair growth. There is a demand for further exploration whose purpose is to seek extracts having ability to promote hair growth effect and fewer side effect. One area that also needs further exploration is to mix or combine the extracts known as having such effect.
Key words: Scalp, Minoxidile, Herbal extracts, Hair growth, C57BL/6mouse
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