| 화장품 소재로서의 발효 옻 추출물에 관한 특성연구 |
| 김정현, 김금란 |
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| Study on the Characteristics of Fermented Rhus verniciflua Stem Bark (FRVSB) as a Cosmetic Raw Material |
| Jung-Hun Kim, Kum Lan Kim |
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| ABSTRACT |
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This study analyzed raw Rhus verniciflua stem bark extract and detoxified fermented Rhus verniciflua stem bark extract in order to figure out their physiological characteristics as cosmetic materials after experimenting their cytotoxicity, anti-inflammatory effects, melanin-inhibitory effects and MMP-1 expression. As a result, the analysis found the followings: In terms of LPS-induced NO-inhibitory activity, amount of COX-2’s mRNA and MMP-1 expressed, the fermented Rhus verniciflua stem bark extract was lower than
the Rhus verniciflua stem bark extract. In particular, inhibition of melanoma cell proliferation over α-MSH and significant reduction in the amount of melanin and tyrosinase protein expressed were observed. The said results reveal that fermented Rhus verniciflua stem bark extract would be very useful as a natural skinwhitening
and anti-aging cosmetic material. |
| Key words:
Cosmetic Material, Ferment, Rhus verniciflua stem bark, COX-2, Melanin, MMP-1
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