| Anti-inflammatory Effect of Dictyopteis undulata in RAW 264.7 Cells |
| Joong Hyun Shim |
| Department of Biohealth-Convergence, Seoul Women’s University, Seoul, Korea |
| Corresponding author: |
Joong Hyun Shim ,Tel: +82 2 970 1142, Fax: +82 2 970 1143, Email: shimjh@swu.ac.kr
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Received: May 30, 2024; Accepted: July 25, 2024. Published online: August 9, 2024. |
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| ABSTRACT |
Purpose:
This study aimed to analyze the anti-inflammatory effects of Dictyopteris undulata extract on skin using RAW 264.7 cells.
Methods:
Its anti-inflammatory effects on RAW 264.7 cells were evaluated by measuring the cell viability, gene expression levels (IL-1α/IL-1β/IL-6 and TNF-α), and nitric oxide (NO)/prostaglandin E2 (PGE2) production.
Results:
Quantitative real-time polymerase chain reaction showed that the D. undulata extract decreased the mRNA levels of IL-1α/IL-1β/IL-6 and TNF-α. Additionally, PGE2/NO detection revealed that D. undulata extract exhibited anti-inflammatory properties.
Conclusion:
D. undulata extract is a potential anti-inflammatory compound. Further study on the anti-inflammatory mechanisms of D. undulata extract would facilitate the development of cosmeceutics and pharmacological treatments.
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| Key words:
Dictyopteris undulata, Anti-inflammation, Nitric oxide, PGE2, Interleukin |
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