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Asian J Beauty Cosmetol > Volume 22(3); 2024 > Article
Asian Journal of Beauty and Cosmetology 2024;22(3): 427-435.
doi: https://doi.org/10.20402/ajbc.2024.0038
주름뼈대그물말에 의한 RAW264.7 세포에서의 항염효과
심중현
서울여자대학교 바이오헬스융합학과, 서울, 한국
Anti-inflammatory Effect of Dictyopteis undulata in RAW 264.7 Cells
Joong Hyun Shim
Department of Biohealth-Convergence, Seoul Women’s University, Seoul, Korea
波状网翼藻对RAW 264.7细胞的抗炎作用
沁重鉉
首尔女子大学生物健康融合学科,首尔,韩国
Corresponding author:  Joong Hyun Shim ,Tel: +82 2 970 1142, Fax: +82 2 970 1143, Email: shimjh@swu.ac.kr
Received: May 30, 2024;  Accepted: July 25, 2024.  Published online: August 9, 2024.
ABSTRACT
Purpose:
This study aimed to analyze the anti-inflammatory effects of Dictyopteris undulata extract on skin using RAW 264.7 cells.
Methods:
Its anti-inflammatory effects on RAW 264.7 cells were evaluated by measuring the cell viability, gene expression levels (IL-1α/IL-1β/IL-6 and TNF-α), and nitric oxide (NO)/prostaglandin E2 (PGE2) production.
Results:
Quantitative real-time polymerase chain reaction showed that the D. undulata extract decreased the mRNA levels of IL-1α/IL-1β/IL-6 and TNF-α. Additionally, PGE2/NO detection revealed that D. undulata extract exhibited anti-inflammatory properties.
Conclusion:
D. undulata extract is a potential anti-inflammatory compound. Further study on the anti-inflammatory mechanisms of D. undulata extract would facilitate the development of cosmeceutics and pharmacological treatments.
Key words: Dictyopteris undulata, Anti-inflammation, Nitric oxide, PGE2, Interleukin
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